Name: Chen Lulu

Professor in Wuhan Union Hospital

Phone: 86-27-85726799


Academic Areas: Endocrinology

Research Interest

Research focus in the areas of obesity, diabetes, diabetic complications in a broad sense, in terms of basic or clinical research and epidemiological studies. Much of my work focuses on the pathogenesis of diabetes, including the etiology of insulin resistance and pancreatic-islet dysfunction.


Doctor--Endocrinology--Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China--2003

Bachelor--Clinical Medicine--Zhongshan Medical University, Guangzhou, China--1988

Oversea Study and Visit

Post Doctoral,Center for Clinical and Basic Research A/S in Copenhagen ,Denmark,1993-01-01-1995-09-30

Visiting Scholar,Columbia University, Diabetes Center, NY,USA,2004-07-01-2004-12-31

Academic Memberships

General Secretary & Standing Committee Member,Chinese Society of Endocrinology ,Chinese Medical Associate,2002-08-01.

Leader,Obesity Study Group ,Chinese Society of Endocrinology,2008-08-01.

Deputy Leader,Fatty Liver Study Group,Chinese Society of Endocrinology,2008-08-01.

Standing Committee Member, Endocrinology and Metabolic Diseases,Chinese Medical Doctor Association,2009-03-03.

Chairman,Hubei Society of Endocrinology,Hubei Medical Associate,2001-05-07.2013-06-13

Vice chairman,Wuhan Society of Endocrinology and Diabetes,Chinese Society of Endocrinology,2001-05-07.

Chairman,Hubei Society of Diabetes,Hubei Medical Associate,2013-06-13.

Honours and Awards

Award of Provincial Science and Technology Advancement Prize,Science and Technology Department of Hubei Province,2007

Award of Science and Technology Advancement Prize,Science and Technology Department of Wuhan,2013

Honours and Awards

[1] Chen LL, Hu X, Zheng J , et al. ,Lipid Overaccumulation and Drastic Insulin Resistance in Adult Catch-up Growth Rats Induced by Nutrition Promotion after Undernutrition.,Metabolism,2010,

[2] Chen LL,Number of circulating endothelial progenitor cells as a marker of vascular endothelial function for type 2 diabetes,Vasc Med,2010,

[3] Chen LL, Yang WH, Zheng J, et al,Effect of catch-up growth after food restriction on the entero-insular axis in rats. ,Nutrition & Metabolism,2010,

[4] Chen LL, Yang WH, Zheng J, et al.,The effect of high-fat diet and catch-up growth on gastric emptying and plasma glucagon-like peptide-1 concentration in rats. ,Chin J Intern Med,2009,

[5] Liao YF, Zeng TS, Chen LL, Li YM, Yu F, Hu LJ, Yue L,Association of a functional polymorphism (C59038T) in GTP cyclohydrolase 1 (GCH1) gene and type 2 diabetic macrovascular disease in the Chinese population,J Diabetes Complications,2009,

[6] Chen LL,Liao YF, Zeng TS, Li YM,Yu F, Li HQ,The number and function of circulating endothelial progenitor cells in different vascular complications of type 2 diabetes.,National Medical Journal Of China,2009,

[7] Chen LL, Hu X, Zheng,J , et al.,Dynamic Changes of Biological Characteristics in Improved Catch-up Growth Rat Model.,Chin J Endocrinol Metab,2009,

[8] Xia WF, Chen LL, Zeng TS.,Study on the effect of estrogen on secretion function and number of pancreatic islet beta cell of ovariectomized rats. ,Chinese Journal of Geriatrics,2009,

[9] Chen LL, Zhang JY, Zhang YP, Wang YB, Wang BP,Improvement of inflammatory responses associated with NF-kB pathway in kidneys from diabetic rats.,Inflammation Research,2008,

[10] Chen LL, Wang Xiaofen, Zheng Juan, Deng Xiulin, Zhang Jiaoyue, Zeng Tianshu.,Differences of glucose metabolism between adipose tissue and skeletal muscle in the early stage of catch-up growth in rats and its mechanism.,Chinese Journal of Endocrinology and Metabolism,,2008,

[11] Chen LL. ,Catch-up growth-a new territory for understanding insulin resistance. ,Chinese Journal of Endocrinology and Metabolism,2008,

[12] Shang J, Chen LL, Xiao FX, Sun H, Ding HC, Xiao H,Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase. ,Acta Pharmacol Sin,2008,

[13] Zhang Jiaoyue, Chen LL.,Early development of visceral fat excess after spontaneous catchup growth in children with low birth weight.,Chinese Journal of Endocrinology and Metabolism,,2008,

[14] Liao YF, Chen LL, Zeng TS, Zheng J, Li HQ. ,Association of the +33371 A/G polymorphism in adiponectin receptor 2 gene with Type 2 diabetes in the Chinese population,J Endocrinol Invest,2007,

[15] Li Yan, Chen LL, Li Huiqing, Wang yongbo, Tian yuan.,Effects of supraphysiologic glucose and palmitate on the content of intracellular triglyceride and expression of FAT/CD36 in β-cells.,Chinese Journal of Diabetes,2008,

[16] Liao Yunfei, Chen LL, Zeng Tianshu, Zheng Juan.,The study on the relevant factors of serum alanine aminotransferase in metabolic syndrome subjects. ,Chinese Journal of Diabetes,2008,

[17] Huang Xiaoqing, Chen LL, Wang Baoping.,Effect of Fenofibrate on Adiponectin Gene Expression and Endothelial Function in Diabetic Rats.,Academic Journal of Guangzhou Medical College,2008,

[18] Chen LL, Deng XQ, Li NX,Effects of calorie restriction on SIRT1 expression in liver of nonalcoholic fatty liver disease: experiment with rats.,Chinese Journal of Diabetes,,2007,

[19] Chen LL, Li Ningxu, Deng Xiangqun.,Effects of Catch-up Growth after Semistarvation on Insulin Resistance in Rats, Acta Nutrimenta Sinica,,2007,

[20] Chen LL, Wang Baoping, Zeng Tianshu, Wang Yongbo, Zhou min, Effects of the insulin treatment on the lipid content in pancreas and on glucose-stimulated insulin secretion(GSIS) in diabetic rats fed high fat diet. ,Chinese Journal of Diabetes,2007,

[21] Wang Yongbo, Chen LL, Zhou Min,Expression and activity of hormone sensitive lipase in islets of diabetic rats, Chinese Journal of Endocrinology and Metabolism,2007,

[22] Wu Hongyan, Chen LL, Zheng Juan, Liao yunfei, Zhou Min,Associations of body mass index with metabolic status and chronic complications in newly-diagnosed type 2 diabetic patients.,Chinese Journal of Endocrinology and Metabolism,2007,

[23] Deng Xiangqun, Chen LL, Li Ningxu.,The chronic hyperglycemia promotes functional impairment of beta cell of islet by lipotoxicity in rats,Chinese Journal of Diabetes,2007,

[24] Deng XQ, Chen LL, Li NX,The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats.,Liver Int,2007,

[25] Wu Hongyan, Chen LL, Zhang Huifang, Zhu Suping.,Associations of waist to height ratio and hypertension among non-obese person. ,Journal of Clinical Cardiology,2007,

[26] Wu HY, Chen LL, Zheng J, Liao YF, Zhou M,Simple anthropometric indices in relation to cardiovascular risk factors in Chinese type 2 diabetic patients,Chin J Physiol,2007,

[27] Chen LL, Zhang JY, Wang BP,Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1,Vascular Pharmacology,,2006,

[28] Chen LL, Wang YB, Zhou M, Wang BP,Effect of insulin treatment on intracellular lipid metabolism in liver of diabetic rats.,Journal of HuazhongUniversity of Science and Technology (Med Sci),2006,

[29] Chen LL, Huiqing Li, Tianshu Zeng, Wenfang Xia, Juan Zheng, Min Zhou.,Effects of Bushen Zhuanggu Formul on interleukin-6 production and bone metabolism of the ovariectomized rats.,Journal of Nanjing Medical University,,2006,

[30] Wang Baoping; Chen LL, Zeng tianshu, Wang yongbo, Xia wenfang.,Effects of the insulin therapy on the insulin content and the expression of insulin in pancreas of diabetic rats fed with prolonged high fat chow.,Chinese Pharmacological Bulletin,2006,

[31] Liu Peiwen, Chen LL, Sun Hui, Zhou Rui, Ma Jie, Wang Bingshuang, Zhang Hongmei, Zhou Yuewei, Geng Mingxia, Wang Wangdong, Wang Wengong, Zeng Qingling, He Fengrong, Tao Yan.,Prevalence and related factors of metabolic syndrome in Wuhan urban adults,Chinese Journal of Endocrinology and Metabolism,2006,

[32] Wu Qian, Chen LL, Wang Baoping, Wei Cuifeng, Zhou Min, Li Yan,Effects of insulin treatment on content of intramyocellular triglyceride and expression of CPTI-β gene in skeletal muscle of diabetic mellitus rats,Chinese Journal of Clinical Pharmacology and Therapeutics,2006,

[33] Deng Xiuling; Yuan Li; Chen LL, Zhou min,Effects of free fatty acids on insulin secretion and expression of sulfonylurea receptor 1 (SUR1) gene in rat pancreatic β cells,Chinese Journal of Diabetes,2006,

[34] Zeng TianShu; Yuan Li; Chen LL.,TNF-α impairs glucose uptake and IRS-1 associated signaling pathway by stimulated insulin in 3T3-L1 adipocytes,Chinese Journal of Immunology,2006,

[35] Shang Jing, Sun Hui, Xiao Fangxi; Chen LL,Hyperinsulinemic-Euglycemic Clamp in Conscious Rats Based on Tail Arterial and Vein Catheterization Technique.,Acta Universitatis Medicinalis Secondae Shanghai,,2006,