Name: Hu Yu

Professor in Wuhan Union Hospital

Phone: 86-27-85726335


Academic Areas: Department of Hematology

Research Interest

The diagnosis and treatment of thrombosis, disseminated intravascular coagulation,angiogenesis in multiple myeloma. At present, his work is focus on the early diagnosis and targeted interfere of thrombosis.


Doctor--Platelet--Union Hospital, Tongji Medical University,Wuhan, China--1989

Master--Platelet--Union Hospital, Tongji Medical University,Wuhan, China--1986

Oversea Study and Visit

Visiting Scholar,Department of Pharmacology,Nagoya University,Japan,1996-04-08-1997-04-08

Academic Memberships

Director,Thrombosis & Hemostasis group,CMDA(Chinese Medical Doctor Association) of Hematology,.

Chairman,Hubei Society of Hematology,CMA,.

Honours and Awards

First prize for scientific and technological progress,Hubei Province,2012-04-09

Yangtze Scholarship,the Ministry of Education P.R.C.,2010-04-09

First prize for scientific and technological progress,Hubei Province,2007-04-09

Second prize for scientific and technological progress,the Ministry of Education P.R.C.,2005-04-09

First prize for scientific and technological progress,Hubei Province,2005-04-09

Second prize for scientific and technological progress,Hubei Province,1999

First prize for scientific and technological progress,the Ministry of Education P.R.C.,1994

Honours and Awards

[1] Zhang B, Sun X, Mei H, Wang Y, Liao Z, Chen J, Zhang Q, Hu Y*, Pang Z, Jiang X.,LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma. ,Biomaterials,2013,

[2] Ai LS, Sun CY, Wang YD, Zhang L, Chu ZB, Qin Y, Gao F, Yan H, Guo T, Chen L, Yang D, Hu Y*.,Gene silencing of the BDNF/TrkB axis in multiple myeloma blocks bone destruction and tumor burden in vitro and in vivo. ,Int J Cancer,2013,

[3] Tang L, Jian XR, Hamasaki N, Guo T, Wang HF, Lu X, Wang QY, Hu Y*,Molecular basis of protein S deficiency in China.,Am J Hematol.,2013,

[4] Chen C, Mei H, Shi W, Deng J, Zhang B, Guo T, Wang H, Hu Y*,EGFP-EGF1-conjugated PLGA nanoparticles for targeted delivery of siRNA into injured brain microvascular endothelial cells for efficient RNA interference.,PLoS One,2013,

[5] Shi W, Mei H, Deng J, Chen C, Wang H, Guo T, Zhang B, Pang Z, Jiang X, Wang X, Lei H, Hu Y*.,The delivery of thrombi-specific nanoparticles incorporating oligonucleotides into injured cerebrovascular endothelium.,Biomaterials,2013,

[6] Sun CY, She XM, Qin Y, Chu ZB, Chen L, Ai LS, Zhang L, Hu Y*.,miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF.,Carcinogenesis,2013,

[7] Tang L, Wang HF, Lu X, Jian XR, Jin B, Zheng H, Li YQ, Wang QY, Wu TC, Guo H, Liu H, Guo T, Yu JM, Yang R, Yang Y, Hu Y*.,Common genetic risk factors for venous thrombosis in the chinese population. ,Am J Hum Genet.,2013,

[8] Lu X, Tang L, Xu K, Ma J, Guo T, Mei H, Yang R, Yu J, Wang Q, Yang Y, Jian X, Hu Y*,Novel association of a PROC variant with ischemic stroke in a Chinese Han population.,Hum Genet.,2013,

[9] Ai LS, Sun CY, Zhang L, Zhou SC, Chu ZB, Qin Y, Wang YD, Zeng W, Yan H, Guo T, Chen L, Yang D, Hu Y*. ,Inhibition of BDNF in Multiple Myeloma Blocks Osteoclastogenesis via Down-Regulated Stroma-Derived RANKL Expression Both In Vitro and In Vivo. ,PLoS One.,2012,

[10] Wei Shi, Heng Mei, Jun Deng, Chen Chen, Huafang Wang, Tao Guo, Bo Zhang, Le Li, Zhiqing Pang, Xinguo Jiang, Shun Shen, Yu Hu*.,A Tissue Factor Targeted Nanomedical System for Thrombi-Specific Drug Delivery. ,Biomaterials.,2012,

[11] L. Tang, X. Lu, J. M. Yu, Q. Y. Wang, R. Yang, T. Guo, H. Mei, Y. Hu*.,PROC c.574_576del Polymorphism: A Common Genetic Risk Factor for Venous Thrombosis in Chinese Population. ,JOURNAL OF THROMBOSIS AND HAEMOSTASIS,2012,

[12] Liang Tang, Tao Guo, Rui Yang, Heng Mei, Huafang Wang, Xuan Lu, Jianming Yu, Qingyun Wang, Yu Hu*.,Genetic Background Analysis of Protein C Deficiency Demonstrates a Recurrent Mutation Associated with Venous Thrombosis in Chinese Population., Plos one.,2012,

[13] Huile Gao, Shuaiqi Pan, Zhi Yang, Shijie Cao, Chen Chen,Xinguo Jiang, Shun Shen, Zhiqing Pang, Yu Hu*.,A cascade targeting strategy for brain neuroglial cells employing nanoparticles modified with angiopep-2 peptide and EGFP-EGF1 protein.,Biomaterials.,2011,

[14] Sun CY, Chu ZB, She XM, Zhang L, Chen L, Ai LS, Hu Y*.,Brain-derived neurotrophic factor is a potential osteoclast stimulating factor in multiple myeloma. ,Int J Cancer,2011,

[15] Heng Mei, Wei Shi, Zhiqing Pang, Yu Hu*, Jun Deng, Huafang Wang, Tao Guo, Xinguo Jiang, Weiyue Lu. ,EGFP-EGF1 protein-conjugated PEG-PLA nanoparticles for tissue factor targeted drug delivery. ,Biomaterials.,2010,