Name: Li Qiubai

Professor in Wuhan Union Hospital

Phone: 86-27-85726387

Email: qiubai.li@yahoo.com

Academic Areas: Department of Hematology

Research Interest

Pathogenesis and target therapy of tumor, especially hematological malignancies

Education

Doctor--Internal Medicine--Wuhan Union Hospital, Wuhan, China--2007

Oversea Study and Visit

Academic Memberships

Honours and Awards

Microvesicles derived from multiple myeloma cells inhibit osteogenesis of bone marrow MSCs and promote disease progression,National Natural Science Foundation of China. No. 81071943,2011

Microvesicles derived from multiple myeloma cells inhibit osteogenesis of BMSCs via horizontal transfer of secreted miRNAs ,National Natural Science Foundation of China. No. 81272624,2013

Pathenolide, a natural proteasome inhibitor against myeloma,Specialized Research Fund for the Doctoral Program of Higher Education of China. No. 200804871109,2008

Expression and role of GILZ in myeloma,National Natural Science Foundation of Hubei. No. 2009cdb143,2009

Honours and Awards

[1] Sun L, Wang H-x, Zhu X-j, Wu P-h, Chen W-q, Zou P*, Li Q-b*, Chen Z-c.,Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro.,Acta Pharmacol Sin,2014,Sun L, Wang H-x, Zhu X-j, Wu P-h, Chen W-q, Zou P*, Li Q-b*, Chen Z-c. Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro. Acta Pharmacol Sin 2014; 35 (3): 381-93.

[2] Liu Y, Zhu X-j, Zeng C, Wu P-h, Wang H-x, Chen Z-c*, Li Q-b*,Microvesicles secreted from human multiple myeloma cells promote angiogenesis.,Acta Pharmacol Sin,2014,Liu Y, Zhu X-j, Zeng C, Wu P-h, Wang H-x, Chen Z-c*, Li Q-b*. Microvesicles secreted from human multiple myeloma cells promote angiogenesis. Acta Pharmacol Sin 2014; 35 (2): 230-38.

[3] Zhu X-j, You Y, Li Q, Zeng C, Fu F-f, Guo A-y, Zhang H-m, Zou P, Zhong Z-d, Wang H-x, Wu Y-h, Li Q-b, Kong F-c, Chen Z-c.,BCR-ABL1-positive microvesicles transform normal hematopoietic transplants through genomic instability: implications for donor cell leukemia.,Leukemia,2014,Zhu X-j, You Y, Li Q, Zeng C, Fu F-f, Guo A-y, Zhang H-m, Zou P, Zhong Z-d, Wang H-x, Wu Y-h, Li Q-b, Kong F-c, Chen Z-c. BCR-ABL1-positive microvesicles transform normal hematopoietic transplants through genomic instability: implications for donor cell leukemia. Leukemia 2014.

[4] Ye H, Liu X, Lv M, Wu Y, Kuang S, Gong J, Yuan P, Zhong Z, Li Q, Jia H, Sun J, Chen Z, Guo AY.,MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia.,Nucleic Acids Res,2012,17 Ye H, Liu X, Lv M, Wu Y, Kuang S, Gong J, Yuan P, Zhong Z, Li Q, Jia H, Sun J, Chen Z, Guo AY. MicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. Nucleic Acids Res 2012,Feb 23.

[5] Li Q, Yu K, Tian X, et al.,17beta-Estradiol overcomes human myeloma RPMI8226 cell suppression of growth, ALP activity, and mineralization in rat osteoblasts and improves RANKL/OPG balance in vitro.,Leuk Res,2009,Li Q, Yu K, Tian X, et al. 17beta-Estradiol overcomes human myeloma RPMI8226 cell suppression of growth, ALP activity, and mineralization in rat osteoblasts and improves RANKL/OPG balance in vitro. Leuk Res. 2009 Sep;33(9):1266-71

[6] Li Q, You Y, Chen Z, Zou P,COX-2/12-LOX dual pathway, a novel strategy for treatment of multiple myeloma?,Bioscience Hypotheses,2009,Li Q, You Y, Chen Z, Zou P. COX-2/12-LOX dual pathway, a novel strategy for treatment of multiple myeloma? Bioscience Hypotheses. 2009;2:81-84.

[7] Li QB, Chen ZC, You Y, Zou P,Small interfering RNA of cyclooxygenase-2 induces growth inhibition and apoptosis independently of Bcl-2 in human myeloma RPMI8226 cells.,Acta Pharmacol Sin.,2007,Li QB, Chen ZC, You Y, Zou P. Small interfering RNA of cyclooxygenase-2 induces growth inhibition and apoptosis independently of Bcl-2 in human myeloma RPMI8226 cells.Acta Pharmacol Sin. 2007 Jul;28(7):1031-6.

[8] Li QB, You Y, Chen ZC, Lü J, Shao J, Zou P.,Role of Baicalein in the regulation of proliferation and apoptosis in human myeloma RPMI8226 cells.,Chin Med J (Engl),2006,Li QB, You Y, Chen ZC, Lü J, Shao J, Zou P. Role of Baicalein in the regulation of proliferation and apoptosis in human myeloma RPMI8226 cells.Chin Med J (Engl). 2006 Jun 5;119(11):948-52.

[9] Li QB, Li L, You Y, et al,A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.,Acta Pharmacol Sin,2009,19 Li QB, Li L, You Y, et al. A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia. Acta Pharmacol Sin. 2009 ;30(10):1471-8.

[10] You Y#, Li QB#, Chen ZC, Li WM, Xia LH, Zhou H, Zou P.,Fludarabine and cytarabine combined chemotherapy followed by transfusion of donor blood stem cells for treating relapse of acute leukaemia after allogeneic haematopoietic stem cell transplantation. ,Chin Med J (Engl),2008,21 You Y#, Li QB#, Chen ZC, Li WM, Xia LH, Zhou H, Zou P.;121(18):1770-4. Fludarabine and cytarabine combined chemotherapy followed by transfusion of donor blood stem cells for treating relapse of acute leukaemia after allogeneic haematopoietic stem cell transplantation. Chin Med J (Engl). 2008

[11] Li Q, Chen Z, You Y, Zou P.,Transient pancytopenia preceding acute lymphoblastic leukemia with positive Philadelphia chromosome., Leuk Res,2008,Li Q, Chen Z, You Y, Zou P. Transient pancytopenia preceding acute lymphoblastic leukemia with positive Philadelphia chromosome. Leuk Res. 2008 Aug;32(8):1317-20.

[12] Zhao ZG, Liang Y, Li K, Li WM, Li QB, Chen ZC, Zou P.,Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases.,Stem Cells Dev,2007,24 Zhao ZG, Liang Y, Li K, Li WM, Li QB, Chen ZC, Zou P. Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases. Stem Cells Dev. 2007 Aug;16(4):637-48.

[13] Qiubai Li, Xiaojian Zhu, Xiaoqing Li, et al,Correlation of Altered Expression of RIZ1 to Diagnosis, Risk Stratification, and Disease Progression in 56 Acute Leukemia Patients,Blood,2009,Qiubai Li, Xiaojian Zhu, Xiaoqing Li, et al. Correlation of Altered Expression of RIZ1 to Diagnosis, Risk Stratification, and Disease Progression in 56 Acute Leukemia Patients.Nov 2009; 114: 2627.