Name: Zhang Xiaoping

Professor in Wuhan Union Hospital

Phone: 86-27-85351625

Email: xiaoping.zhang2008@gmail.com

Academic Areas: Department of Urology

Research Interest

Urological Cancer

Education

Doctor--Multidrug resistance of bladder cancer--Tongji Medical College, Wuhan, Hubei, P.R. China--1999

Master--Prostatitis--Tongji Medical College, Wuhan, Hubei, P.R. China--1994

Oversea Study and Visit

Post Doctoral,BIDMC & MGH, Harvard Medical School,USA,2002-08-05-2007-09-30

Post Doctoral,Dept. of Cell Biology, University of Cincinnati,USA,2001-09-10-2002-07-31

Academic Memberships

Honours and Awards

Honours and Awards

[1] Xuan-Yu Chen, ...... and Xiao-Ping Zhang (Corresponding Author)., MiR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes. , Journal of Cancer Research and Clinical Oncology.,2014,

[2] Xuan-Yu Chen, ...... and Xiao-Ping Zhang (Corresponding Author).,miR-141 is A Key Regulator of Renal Cell Carcinoma Proliferation and Metastasis by Controlling EphA2 Expression., Clinical Cancer Research. ,2014,

[3] Hongmei Yang, ...... and Xiao-Ping Zhang (Corresponding Author).,Inhibition of PP2A Activity Confers a TRAIL-sensitive Phenotype During Malignant Transformation. ,Molecular Cancer Res.,2014,

[4] Xuegang Wang, ...... and Xiao-Ping Zhang (Corresponding Author).,microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis. ,Oncology Reports.,2013,

[5] Xiaoping Zhang, Xu Huang, Aria F. Olumi. ,Repression of NF-kB and Activation of AP-1 Enhance Apoptosis in Prostate Cancer Cells. ,International Journal of Cancer. ,2009,

[6] Xiaoping Zhang, Hongmei Yang, Liang Zhang, Xu Huang, Hasan Otu, Towia A. Libermann, William C. DeWolf, Roya Khosravi-Far, Aria F. Olumi., c-Fos as a Pro-Apoptotic Agent in TRAIL-induced Apoptosis in Prostate Cancer Cells. ,Cancer Research.,2007,

[7] Xiaoping Zhang, Wenhua Li, Aria F. Olumi., Low-dose 12-O-Tetradecanoylphorbol-13-Acetate Enhances TRAIL-induced Apoptosis in Prostate Cancer Cells. . ,Clinical Cancer Research,2007,

[8] Xiaoping Zhang, Wenhua Li, Aria F. Olumi. ,Overcoming Resistance to Trail-Induced Apoptosis in Prostate Cancer by Regulation of c-FLIP. , Methods in Enzymology. ,2008,

[9] Xiaoping Zhang, Tai-Guang Jin, Hongmei Yang, William C. DeWolf, Roya Khosravi-Far and Aria F. Olumi. , Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to TRAIL-mediated apoptosis in prostate cancer.., Cancer Research,2004,

[10] Monomani Ganapathy, Rita Ghosh, Jiangping Xie, Xiaoping Zhang, Roble Bedolla, Roble Bedolla, John Schoolfield, I-Tien Yeh, Dean A Troyer, Aria F. Olumi and Addanki P. Kumar., Involvement of FLIP in 2-methoxyestradiol induced tumor regression in transgenic adenocarcinoma of mouse prostate (TRAMP) model. ,Clin Cancer Res. ,2009,

[11] Haifeng Yang, Yoji Andrew Minamishima, Qin Yan, Susanne Schlisio, Benjamin L. Ebert, Xiaoping Zhang, Liang Zhang, William Y. Kim, Aria F. Olumi, and William G. Kaelin, Jr ., pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2. ., Molecular Cell,2007,

[12] Xu Huang, Xiaoping Zhang, Benyamin Farahvash, Aria F. Olumi. ,NOVEL TARGETED PRO-APOPTOTIC AGENTS FOR TREATMENT OF PROSTATE CANCER. ,Journal of Urology.,2007,

[13] Lianjie Li, Liang Zhang, Xiaoping Zhang, Qin Yan, Yoji Andrew Minamishima, Aria F. Olumi, Mao Mao, Steven Bartz, and William G. Kaelin Jr., Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. ,Mol Cell Biol. ,2007,

[14] Wenhua Li, Xiaoping Zhang, Aria F. Olumi., MG-132 sensitizes TRAIL-resistant prostate cancer cells by activating c-Fos/c-Jun heterodimers and repressing c-FLIP(L). ,Cancer Research.,2007,

[15] Liang Zhang, Xiaoping Zhang, Glen W. Barrisford, Aria F. Olumi. ,Lexatumumab (TRAIL-receptor 2 mAb) induces expression of DR5 and promotes apoptosis in primary and metastatic renal cell carcinoma in a mouse orthotopic model. ,Cancer Lett. ,2007,

[16] Christopher N. Mayhew, Lisa M. Perkin, Xiaoping Zhang, Julien Sage, Tyler Jacks and Erik S Knudsen., Discrete signaling pathways participate in RB-dependent responses to chemotherapeutic agents., Oncogene,2004,

[17] Steven P. Angus, Linda J. Wheeler, Sejal A. Ranmal, Xiaoping Zhang, Michael P. Markey, Christopher K. Mathews, and Erik S. Knudsen. ,Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication., J Biol Chem.,2002,