Name: Xiang Hong-Bing

Professor in Tongji Hospital

Phone: 86-27-15071379880

Email: xhbtj2004@163.com

Academic Areas: Department of anesthesiology and pain medicine

Research Interest

My research focuses on itch, pain, and neuronal phenotype and biochemically anatomical study of the exact targets for deep brain stimulation by using virus-mediated multi-synaptic tracer technique and transgenic mouse.

Education

Doctor--Department of anesthesiology and pain medicine-- Tongji Medical College, Huazhong University of Science and Technology--2004

Oversea Study and Visit

Post Doctoral,Oregon Health and Science University,USA,2010-06-16-2011-07-29

Visiting Scholar,Yale University School of Medicine,USA,2009-11-06-2010-06-16

Academic Memberships

Honor Associate professor,Department of anesthesiology,Hong Kong University,2014-03-18.2016-11-04

Honours and Awards

Honours and Awards

[1] 1.Hong-Bing Xiang*, Wen-Zhen Zhu, Xue-Hai Guan, Da-Wei Ye. The cuneiform nucleus may involve in the regulation of skeletal muscle tone by motor pathway: A virally mediated transsynaptic tracing study in surgically sympathectomized mice. Brain. 2013 Oct;136(Pt 10):e251 (2013 IF=10.2) 2.Hong-Bing Xiang*, Cheng Liu, Da-Wei Ye, Wen-Zhen Zhu. Possible mechanism of spinal T9 stimulation-induced acute renal failure: A virally mediated transsynaptic tracing study in transgenic mouse model. Pain Physician. 2013;16(1):E47-E49 (2013 IF=4.766) 3.Hong-Bing Xiang*, Wen-Zhen Zhu, Hui-Lian Bu, Tao-Tao Liu, Cheng Liu. Possible mechanism of the subthalamic nucleus stimulation-induced acute renal failure: A virally mediated transsynaptic tracing study in transgenic mouse model. Mov Disord. 2013 Dec;28(14):2037-8. (2013 IF=5.6) 4. Qiu Qiu, Rong-Chun Li, De-Fang Ding, Cheng Liu, Tao-Tao Liu, Xue-Bi Tian, Hong-Bing Xiang*, Chi-Wai Cheung. Possible mechanism of regulating glucose metabolism with subthalamic nucleus stimulation in parkinson's disease: a virally mediated trans-synaptic tracing study in transgenic mice. Parkinsonism & Related Disorders. 2014Apr;20(4):468-70.. DOI 10.1016/j.parkreldis.2013.12.008 (2014, IF=4.126) 5. Li Feng, Tao-Tao Liu, Da-Wei Ye, Qiu Qiu, Hong-Bing Xiang*, Chi-Wai Cheung*. Stimulation of the dorsal portion of subthalamic nucleus may be a viable therapeutic approach in pharmacoresistant epilepsy: A virally mediated transsynaptic tracing study in transgenic mouse model. Epilepsy & Behavior. Volume 31, February 2014, Pages 114–116. 6. Liu TT, Guo QQ, An K, Zhang Y, Tian XB, Li RC, Xiang HB*, Wang P*. The optimal acupoint for acupuncture stimulation as a complementary therapy in pediatric epilepsy. Epilepsy Behav. Volume 31, February 2014, Pages 387–389 doi: 10.1016/j.yebeh. 2013.10.015. [Epub ahead of print] No abstract available. IF=2.061 7. Bu H, Shu B, Gao F, Liu C, Guan X, Ke C, Cao F, Hinton AO Jr, Xiang H, Yang H, Tian X, Tian Y*. Spinal IFN-γ-induced protein-10 (CXCL10) mediates metastatic breast cancer-induced bone pain by activation of microglia in rat models. Breast Cancer Res Treat. 2014 Jan;143(2):255-63. doi: 10.1007/s10549-013-2807-4. Epub 2013 Dec 13. 8. Da-Wei Ye, Cheng Liu, Tao-Tao Liu, Xue-Bi Tian, Hong-Bing Xiang. Motor cortex- periaqueductal gray-spinal cord neuronal circuitry may involve in modulation of nociception: A virally mediated transsynaptic tracing study in spinally transected transgenic mouse model. PLoS One. 2014, 9(2): e89486. (2012年IF= 3.73) 9. Dawei Ye, Huilian Bu, Genhua Guo, Bin Shu, Wei Wang, Xuehai Guan, Hui Yang, Xuebi Tian, Hongbing Xiang, Feng Gao*. Activation of CXCL10/CXCR3 Signaling Attenuates Morphine Analgesia: Involvement of Gi Protein. Journal of Molecular Neuroscience. 2014 Jan 12. [Epub ahead of print] 10. Hong-Bing Xiang, Tao-Tao Liu, Xue-Bi Tian, Wen-Zhen Zhu. Therapeutic mechanism of subthalamic nucleus stimulation for refractory epilepsy involved in melanocortin-4 receptor signaling. Molecular & Cellular Epilepsy. 2014; 1: 13-18. 11. Xu B, Guan XH, Yu JX, Lv J, Zhang HX, Fu QC, Xiang HB, Bu HL, Shi D, Shu B, Qin LS, Manyande A, Tian YK. Activation of spinal phosphatidylinositol 3-kinase/protein kinase B mediates pain behavior induced by plantar incision in mice. Exp Neurol. 2014 May; 255: 71-82. 12. Qingxiong Hong, Bing Ke, Hui Yang, Tao-Tao Liu, Wei Mei, Hong-Bing Xiang, Guangguang Fang. Cuneiform nucleus stimulation as adjunct treatment for intractable epilepsy: A virally mediated trans-synaptic tracing study in spinally transected transgenic mice. Epilepsy & Behavior. Volume 33, April 2014, Pages 135–137. 13. Qingxiong Hong, Guangguang Fang, Tao-Tao Liu, Xue-Hai Guan, Hong-Bing Xiang, Zhiheng Liu. Posterior pedunculopontine tegmental nucleus may involve in visual complaints with intractable epilepsy. Epilepsy & Behavior. 2014May 1;34C:55-57 14. Bing Ke, Tao-Tao Liu, Cheng Liu, Hong-bing Xiang, Jun Xiong*. Dorsal subthalamic nucleus electrical stimulation for drug/treatment-refractory epilepsy may modulate melanocortinergic signaling in astrocytes. Epilepsy & Behavior. 2014 July, 36: 6–8. 15. Hong-Bing Xiang, Cheng Liu, Tao-Tao Liu, Jun Xiong*. Central circuits regulating the sympathetic outflow to lumbar muscles in spinally transected mice by retrograde transsynaptic transport. International Journal of Clinical and Experimental Pathology. 2014, 7(6): 2987-2997. (IF=1.783) 16. Da-Wei Ye, Cheng Liu, Xue-Bi Tian, Hong-Bing Xiang*. Identification of neuroanatomic circuits from spinal cord to stomach in mouse: Retrograde retrograde transneuronal viral tracing study. International Journal of Clinical and Experimental Pathology. 2014, 7(8): 5343-5347 17. Yan Hao, Xue-Bi Tian, Cheng Liu, Hong-Bing Xiang*. Retrograde tracing of medial vestibular nuclei connections to the kidney in mice. Int J Clin Exp Pathol 2014;7(8): 5348-5354 18. Yan Hao, Xue-Hai Guan, Tao-Tao Liu, Zhi-Gang He, Hong-Bing Xiang*. Hypothesis: The central medial amygdala may be implicated in sudden unexpected death in epilepsy by melanocortinergic–sympathetic signaling. Epilepsy & Behavior. Volume 41, December 2014, Pages 30–32 19. De-Fang Ding, Rong-Chun Li, Qiu-Ju Xiong, Ling Zhou, Hong-Bing Xiang*. Pulsed radiofrequency to the great occipital nerve for the treatment of intractable postherpetic itch: a case report. Int J Clin Exp Med 2014;7(10):3497-3500. 20. Cheng Liu, Da-Wei Ye, Xue-Hai Guan, Rong-Chun Li, Hong-Bing Xiang*, Wen-Zhen Zhu*. Stimulation of the pedunculopontine tegmental nucleus may affect renal function by melanocortinergic signaling. Medical Hypotheses. 2013;81(1):114-116 (2012 IF=1.054) 21. Hong-Bing Xiang*, Wen-Zhen Zhu, Xue-Hai Guan, Da-Wei Ye. Possible mechanism of deep brain stimulation for the pedunculopontine nucleus-induced urinary incontinence: A virally mediated transsynaptic tracing study in transgenic mouse model. Acta Neurochirurgica. 2013,155(9): 1667-1669. (2012 IF=1.546) 22. Tao-Tao Liu, Jueping Feng, Hui-Lian Bu, Cheng Liu, Xue-Hai Guan, Hong-Bing Xiang*. Stimulation for the compact parts of pedunculopontine nucleus: An available therapeutic approach in intractable epilepsy. Epilepsy & behavior.. 2013 Oct; 29(1): 252-253 (2012 IF= 1.844) 23. Xue-Bi Tian, Jueping Feng, Hui-Lian Bu, Cheng Liu, Tao-Tao Liu, Hong-Bing Xiang*, Zhi-Heng Liu*. The change of cerebral glucose metabolism generated by electroacupuncture may predict the outcome of stimulation for anterior nucleus thalamus in refractory epilepsy. Epilepsy & behavior. 2013 Nov;29(2):427-429 10.1016/j.yebeh.2013.08.015(2012 IF= 1.844) 24. Xue-Bi Tian, Rong-Chun Li, Hui-Lian Bu, Cheng Liu, Tao-Tao Liu, Hong-Bing Xiang*, Chuan-Jian Lu*. The mechanism of electroacupuncture for predicting the efficacy of deep brain stimulation in pharmacoresistant epilepsy may be involved in the melanocortinergic signal. Epilepsy & behavior. 2013 Dec;29(3):594-6. doi: 10.1016/j.yebeh.2013.08.031. Epub 2013 Oct 8.(2012 IF= 1.844) 25. Da-Wei Ye, De-Fang Ding, Tao-Tao Liu, Xue-Bi Tian, Cheng Liu, Rong-Chun Li, Hong-Bing Xiang*, Chi-Wai Cheung*. The optimal segment for spinal cord stimulation in intractable epilepsy: A virally mediated trans-synaptic tracing study in spinally transected transgenic mice. Epilepsy & behavior. 2013 Dec;29(3):599-601. doi: 10.1016/j.yebeh. 2013.09.021. Epub 2013 Oct 18.(2012 IF= 1.844) 26. Tao-Tao Liu, Qing-Qing Guo, Ke An, Yi Zhang, Xue-Bi Tian, Rong-Chun Li, Hong-Bing Xiang*, Peng Wang*. The optimal acupoint for acupuncture stimulation as a complementary therapy in pediatric epilepsy. Epilepsy & behavior. 2013 Nov 11. doi:pii: S1525-5050 (13)00548-9. 10.1016/j.yebeh.2013.10.015. [Epub ahead of print](2012 IF= 1.844) 27. Xuchu Pan,Yongtang Song, Cheng Liu,HongBing Xiang*. Melanocortin-4 receptor expression in the rostral ventromedial medulla involved in modulation of nociception. Journal of Huazhong University of Science and Technology (Medical Sciences). 2013, 33(2): 195-198(2012 IF= 0.581)